Bote blanco de Arthrokun perro: suplemento nutricional para el manejo sintomático de los procesos articulares degenerativos.

Arthrokun (dogs – 260 g)


For the symptomatic management of articular degenerative processes.

  • Promotes cartilage regeneration
  • Protects cell membranes from oxidative damage caused by inflammation
  • Minimizes inflammation, slows the joint degeneration, and soothes the pain

Know more about

Available: 657 in stock


Fish oil (sardine), flavoring byproduct (hydrolyzed pork and chicken liver), glucosamine HCI (7.7%), chondroitin sulphate (3.3%).

Nutritional additives

Natural products: Curcuma longa L.: Turmeric extract – 25 000 mg/kg; Flavourings: Piperine – 250 mg/kg; Vitamins: Vitamin C – 11 750 mg/kg, Vitamin E – 12 500 IU/kg; Trace elements: Selenium (sodium selenite) – 8.8 mg/kg.

Analytical constituents

Crude protein 7.90%; Crude fibres 0.00%; Crude fat 47.86%; Crude ash 20.58%; Omega 3 fatty acids 15.00%; Omega 6 fatty acids 3.13%

How do its active ingredients work?


Vitamin E

The inflammation generates a large amount of free radicals, which themselves accelerate the inflammatory process. Vitamin E is one of the most effective antioxidants for protecting polyunsaturated fatty acids of cell membranes from oxidation. Vitamin E inhibits lipid oxidation by scavenging peroxyl radicals much faster than these radicals can react with fatty acids or proteins from adjacent cell membranes.


Vitamin C

It is the most powerfull reducing agent available for cells. Vitamin C regenerates glutathione enzyme, quenches free radicals both intra and extracellularly, and protects against free radical-mediated protein inactivation associated with oxidative bursts of neutrophils.



It acts as cofactor of glutathione peroxidase, an antioxidant enzyme that protects tissues against oxidative stress, by catalyzing the reduction of hydrogen peroxides and organic hydroperoxides and by regenerating vitamin E.



It reduces cartilage degradation (inhibits metalloproteinases) and promotes cartilage regeneration (stimulates the production of glycosaminoglycans and the synthesis of collagen.



It possesses an abolic effects on the cartilage including stimulation of glycosaminoglycan and proteoglycanproduction. Moreover, it also acts by inhibiting the activity of degradative cartilage enzymes (aggrecanases and metalloproteinases).


Omega 3 fatty acids

They improve the clinical signs of osteoarthritis, clinical orthopedic examination, gait analysis of ground reaction forces, alongwith a decrease in pain. Being a clear example of the application of nutrigenomics in the nutrition of dogs and cats, eicosapentaenoic acid (EPA) inhibits the upregulation of aggrecanases, by blocking the signal at the level of messenger RNA, reducing the articular cartilage degradation. Moreover, omega 3 fatty acids modulate eicosanoid production. Eicosanoids resulting from omega-3 fatty acid metabolism are less stimulants of the inflammatory response than those resulting from omega-6 fatty acids. Moreover, they are the precursors of resolvins and protectins, counter-regulatory inflammatory substances that serve as agonists for endogenous anti-inflammatory mechanisms and significantly act in the resolution of inflammation.



Its anti-inflammatory properties appears to be mediated through the inhibition of induction of important enzymes that mediate inflammatory processes like COX-2, LOX, and iNOS production of cytokines such as interferon-gamma and tumor necrosis factor, and activation of transcription factors like NF-κB and AP-1.



It increases curcumin bioavailability (by 20-fold), due to piperine’s inhibition of hepatic glucuronidation and intestinal metabolism of curcumin.

  • Osteoarthritis that occurs with lameness.
  • Animals with risk of developing osteoarthritis:
    • Medium risk: Large and fast-growing breeds with genetic predisposition to develop orthopedic developmental diseases.
    • High risk: Animals with existing orthopedic diseases, older animals,or patients who suffer traumas or obesity.
  • Animals with a high level of activity.


It is not recommended the use of ARTHROKUN in case of:

  • Patients with clotting problems, co-administration with drugs that inhibit platelet-aggregation, or hemorrhagic processes.
  • Situations with subclinical iron deficiency or other diseases associated with iron.

Daily recommendation to be added to the food (on top). This dose can be divided into different shots:

Weight Spoons* Amount for
<10 kg 0.5 2 months
10-20 kg 1.0 1 month
20-30 kg 1.5 20 days
>30 kg 2.0 15 days

*8.3 g per spoon


During how much time?

  • Osteoarthritis: Administration is recommended for at least 1 monthand as long as the symptoms persist.
  • Osteoarthritis with controlled symptomatology: Reduce the daily dose up to half as maintenance.
  • Animals with medium risk of developing osteoarthritis: Administer half of the recommended daily dose as a preventive treatment.
  • Animals at high risk of developing osteoarthritis: Start the administration before the onset of symptoms a sa preventive treatment.
  • Animals with a high level of activity: Administer half of the recommended daily dose as a preventive treatment.